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Medically monitored care

Ketamine Infusion Therapy in Bangalore

Dr. Nitish Mandal provides medically monitored ketamine infusion therapy in Bangalore at his Koramangala and J.P. Nagar pain clinics, for selected patients with difficult-to-treat chronic pain and treatment-resistant depression. A first visit is required before an infusion is recommended.

Depression

Depression

Widespread pain

Widespread pain

Emotional trauma

Emotional trauma

Nerve pain

Nerve pain

Who provides ketamine infusion therapy in Bangalore?

Dr. Nitish Mandal, Consultant Pain Physician, provides medically monitored ketamine infusion therapy in Bangalore. Infusions may be considered for selected patients at Koramangala Pain Clinic and J.P. Nagar Pain Clinic.

This page describes one treatment that may be considered after diagnosis. Care starts with the source of the pain, or with a separate assessment when the question is treatment-resistant depression. Ketamine is not presented as a service you simply book.

What is ketamine infusion therapy?

Ketamine infusion therapy at this clinic is a medically monitored, low-dose IV session of about one hour. Low-dose ketamine is mixed with saline and given slowly through a cannula in the arm, with the doctor present throughout.

It may be considered for selected patients with severe, persistent, refractory chronic pain, including fibromyalgia, neuropathic pain, and Complex Regional Pain Syndrome (CRPS). Treatment-resistant depression is assessed on a separate pathway.

The clinics use specialised protocols in a medically monitored setting. Suitability is confirmed in clinic, not from a webpage.

Who may be considered for ketamine infusion therapy?

Ketamine infusion may be considered for selected patients whose chronic pain or treatment-resistant depression has not responded adequately to conventional treatment.

This is not a first-line treatment for every person with fibromyalgia, nerve pain, CRPS, or depression. It is a selected option for difficult-to-treat cases after assessment.

The decision depends on:

  • the diagnosis
  • previous treatments
  • medical history
  • current medicines
  • psychiatric history where relevant
  • the potential risks of ketamine

A consultation is required before an infusion is recommended. The first visit is to understand the pattern of pain or mood symptoms, then decide whether an infusion belongs in the plan.

What is a ketamine infusion for fibromyalgia and nerve pain?

Chronic pain conditions such as fibromyalgia, CRPS, and severe neuropathic pain can be debilitating. Standard tablets and other treatments often fail to give enough relief.

Ketamine may be considered in selected patients with these conditions, particularly when pain is severe, persistent, and refractory to other treatments.

The evidence is not equally strong for every condition. It is generally stronger in some refractory neuropathic pain and CRPS settings. Evidence for fibromyalgia remains more limited or mixed. That is why the fibromyalgia page lists ketamine as one option for selected, difficult cases after the pattern of pain and sleep is understood, not as the opening of the visit.

Low-dose IV ketamine is thought to act mainly as an NMDA-receptor antagonist. In pain care, that mechanism is discussed as a way to reduce central sensitisation and abnormal pain transmission. It is not described here as resetting the brain or resetting pain receptors.

Whether an infusion belongs in the plan is confirmed in clinic.

Monitoring during a ketamine infusion session
Resting calmly after an infusion

When is ketamine discussed for treatment-resistant depression?

Treatment-resistant depression is a separate pathway from chronic-pain care. Ketamine may be discussed for selected people who have not responded adequately to standard antidepressants. It may also be discussed when depression is severe and has not responded to usual care. It is not a first-line depression treatment, and it is not a cure.

Ketamine is described as acting on NMDA receptors in the brain. IV ketamine and intranasal esketamine (Spravato) are related medicines, but they are not the same treatment.

This clinic setting is not a replacement for emergency psychiatric care. If you have active suicidal thoughts, feel you may act on them, or are in immediate danger, seek urgent emergency or psychiatric care rather than waiting for a ketamine consultation.

Which conditions may be considered?

Ketamine infusion therapy may be considered in selected, difficult-to-treat cases. It is not presented as a standard treatment for every person with these labels.

  • Fibromyalgia
  • Neuropathic pain
  • Complex Regional Pain Syndrome (CRPS)
  • Treatment-resistant depression

    Separate assessment pathway

Is IV ketamine the same as esketamine (Spravato)?

No. Ketamine and esketamine are related medicines but are not the same treatment.

Esketamine is a specific ketamine-derived medication with approved psychiatric indications in some countries, and in those settings it has a restricted administration and monitoring framework. IV ketamine itself is not the same product, and it may be used off-label in selected clinical situations after medical assessment.

This page is about medically monitored IV ketamine infusion therapy in Bangalore. It is not a guide to esketamine prescribing, and it does not treat the two as interchangeable.

What are the risks of ketamine infusion?

Ketamine is given here only as a medically supervised clinic infusion. A low dose and a slow infusion do not mean the treatment is risk-free. Monitoring matters because important effects can occur during and after the session.

  • transient sedation
  • dissociation or perceptual changes
  • blood-pressure changes
  • nausea or vomiting
  • dizziness
  • temporary impairment of judgment or coordination
  • rare but clinically important adverse events, including breathing-related concerns in susceptible patients

These effects are why the doctor monitors the session, why the setting is not the same as recreational use, and why going home is decided after the infusion, not in advance. Ketamine also has recognised misuse and dependence potential. That is another reason it is not given as an unsupervised or walk-in treatment.

Is clinic ketamine the same as recreational use?

No. The clinic uses a low dose, given as a slow medical infusion, with continuous monitoring by the doctor. That setting is not the same as recreational use.

Ketamine has misuse and dependence potential, which is why treatment should be prescribed and administered under medical supervision. Repeated medically indicated infusions are not, by themselves, evidence of addiction. Before further sessions are recommended, the patient's response, risks, medical history, and ongoing clinical need are reassessed.

Some people need further sessions. The need is reviewed as recovery continues. Further treatment is a clinical decision, not a standing booking.

What happens during a ketamine session?

  1. You are positioned comfortably, and an IV cannula is inserted into an arm vein.
  2. Low-dose ketamine is mixed with saline and infused slowly over approximately one hour.
  3. Soothing music is encouraged. The doctor monitors you throughout the session.
  4. The cannula is removed, and a small bandage is applied.

An infusion generally lasts approximately one hour. Time in clinic can be longer than the infusion itself because of preparation and monitoring afterwards. Some patients may require more than one session. The number and spacing of infusions depend on the diagnosis, response, medical history, risks and treatment plan, and are reassessed as treatment continues. Going home the same day is common, but it is decided after the session, not from this page.

How much does ketamine infusion therapy cost in Bangalore?

The cost of ketamine infusion therapy depends on the clinical plan and requirements. The current consultation and treatment charges are confirmed by the clinic before treatment.

Where can I get ketamine infusion therapy in Bangalore?

Dr. Nitish Mandal provides medically monitored ketamine infusions at two Bangalore (Bengaluru) pain clinics. Prior appointment is preferred.

Pain clinic reception in Bangalore

Koramangala Pain Clinic

Sulochana Building, 365, 1st Floor, 1st Cross Rd, 3rd Block, Koramangala, Bengaluru, Karnataka 560034. Near Santhosapuram 1st Cross Road. Convenient for Indiranagar, HSR Layout, and Central Bangalore.

Phone: +91 76249 97990

All days, 10 AM to 2 PM.

J.P. Nagar Pain Clinic

1st Floor, #15, Bannerghatta Rd, Sarakki Industrial Layout, 3rd Phase, J.P. Nagar, Bengaluru, Karnataka 560076. Above the MG showroom and below Cult Gym. Convenient for South Bangalore and Bannerghatta Road.

Phone: +91 99808 04636

Monday to Saturday, 4 PM to 6 PM.

WhatsApp: +91 80502 87888. Email: teamdrnitish@gmail.com.

Common questions about ketamine infusion therapy

What is ketamine infusion therapy?
Ketamine infusion therapy is a medically monitored, low-dose IV ketamine session, usually about one hour, given in clinic after a consultation. At this practice it may be considered for selected patients with difficult-to-treat chronic pain and, on a separate pathway, selected treatment-resistant depression.
Who provides ketamine infusion therapy in Bangalore?
Dr. Nitish Mandal, Consultant Pain Physician, provides medically monitored ketamine infusion therapy at Koramangala Pain Clinic and J.P. Nagar Pain Clinic.
Who is a candidate for ketamine infusion therapy?
A candidate is a selected patient whose chronic pain or treatment-resistant depression has not responded adequately to conventional treatment, and whose medical history, current medicines, and risks make a monitored infusion appropriate. The decision depends on the diagnosis, previous treatments, and potential risks of ketamine. That decision is made at a first visit, not from this page.
How does ketamine infusion work for chronic pain?
Ketamine is thought to act on NMDA receptors. In chronic pain, this is discussed as a way to reduce central sensitisation and abnormal pain transmission. It may be considered when pain is severe, persistent, and refractory to other treatments. It is not described as resetting the brain or pain receptors.
How long does a ketamine infusion take?
An infusion generally lasts approximately one hour. You are monitored throughout. Time in clinic can be longer than the infusion itself because of preparation and observation afterwards.
How many ketamine infusions might I need?
There is no fixed number for every patient. Some patients may require more than one session. The number and spacing of infusions depend on the diagnosis, response, medical history, risks and treatment plan, and are reassessed as treatment continues.
What are the side effects of ketamine infusion?
Effects can include transient sedation, dissociation or perceptual changes, blood-pressure changes, nausea or vomiting, dizziness, and temporary impairment of judgment or coordination. Rare but clinically important adverse events can occur. This is why the session is medically monitored.
Is ketamine infusion safe?
A monitored low-dose clinic infusion is not the same as unsupervised or recreational use. Safety depends on patient selection, medical history, current medicines, and continuous monitoring. The treatment is not risk-free. Going home is decided after the session.
Is IV ketamine the same as esketamine (Spravato)?
No. Ketamine and esketamine are related medicines but are not the same treatment. Esketamine is a specific ketamine-derived medication with approved psychiatric indications in some countries. IV ketamine may be used off-label in selected clinical situations, depending on the diagnosis and medical assessment.
Can ketamine help treatment-resistant depression?
It may be discussed for selected people who have not responded adequately to standard antidepressants. It is not a cure, not a first-line treatment, and not a replacement for emergency psychiatric care. Seek urgent help if you are in crisis.
Can ketamine help fibromyalgia?
It may be considered in selected, difficult fibromyalgia cases after the pain and sleep pattern are understood. Evidence for fibromyalgia is more limited or mixed than for some refractory neuropathic pain and CRPS settings. It is not the first sentence of the visit.
Can ketamine help neuropathic pain?
It may be considered in selected patients with severe, persistent, refractory neuropathic pain, including some CRPS presentations. Suitability depends on the diagnosis and what has already been tried.
Where can I get ketamine infusion therapy in Bangalore?
Dr. Nitish Mandal provides medically monitored ketamine infusions at Koramangala Pain Clinic (+91 76249 97990) and J.P. Nagar Pain Clinic (+91 99808 04636). WhatsApp is +91 80502 87888. Book a first visit first.
Can I book ketamine without a first visit?
No. The first visit is to understand the pattern of pain or mood symptoms, then decide whether an infusion belongs in the plan.
Will I go home the same day?
An infusion generally lasts about one hour. You are monitored throughout. Going home is decided after the session, not from a webpage.
Is ketamine a cure for depression?
No. It may be discussed for selected treatment-resistant depression in a monitored setting. It does not replace emergency psychiatric care if you have active suicidal thoughts. Seek urgent help if you are in crisis.
Can ketamine be addictive?
Ketamine has misuse and dependence potential, which is why treatment should be prescribed and administered under medical supervision. Repeated medically indicated infusions are not, by themselves, evidence of addiction. Before further treatment is recommended, response, risks, medical history, and ongoing clinical need are reassessed.
Is this the same as recreational ketamine use?
No. Clinic treatment uses a low dose as a slow medical infusion, with the doctor present. That setting is not the same as recreational use.
How much does ketamine infusion therapy cost in Bangalore?
The cost of ketamine infusion therapy depends on the clinical plan and requirements. The current consultation and treatment charges are confirmed by the clinic before treatment.

Medically reviewed by Dr. Nitish Mandal, Consultant Pain Physician, Bangalore. MBBS, MD (Anaesthesiology), FIPM, TIPM (Nashville). Clinics: Koramangala Pain Clinic and J.P. Nagar Pain Clinic. Last reviewed: September 2026.

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Is this a ketamine clinic?

No. Dr. Nitish Mandal is a Consultant Pain Physician in Bangalore. Ketamine infusion therapy may be considered for selected difficult-to-treat chronic pain, with a separate pathway for selected treatment-resistant depression.

Which conditions may be considered?

Selected, refractory cases of fibromyalgia, neuropathic pain, and CRPS, and selected treatment-resistant depression. Evidence is not equally strong for every condition. A first visit is required before an infusion is recommended.

How long is a session?

An infusion generally lasts approximately one hour, with the doctor monitoring throughout. Going home is decided after the session.

Ask about ketamine infusion therapy